Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses
Abstract Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse mode...
Main Authors: | Katelynn A. Milora, Siva R. Uppalapati, Julio C. Sanmiguel, Wei Zou, Liselotte E. Jensen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05363-4 |
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