Synergistic effect of cisplatin chemotherapy combined with fractionated radiotherapy regimen in HPV-positive and HPV-negative experimental pharyngeal squamous cell carcinoma

Abstract HPV infection renders oropharyngeal squamous cell carcinomas more radiosensitive, which results in a favorable prognosis for HPV-positive patients treated with radiation alone or with concurrent platinum-based chemotherapy. The degree of radiosensitivity in fractionated regimens has not yet...

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Bibliographic Details
Main Authors: Simona Kranjc Brezar, Ajda Prevc, Martina Niksic Zakelj, Andreja Brozic, Maja Cemazar, Primoz Strojan, Gregor Sersa
Format: Article
Language:English
Published: Nature Publishing Group 2020-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-58502-9