IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children.

IFNγ/IL-10 co-producing cells dominate the CD4 response to malaria in highly exposed children.

Although evidence suggests that T cells are critical for immunity to malaria, reliable T cell correlates of exposure to and protection from malaria among children living in endemic areas are lacking. We used multiparameter flow cytometry to perform a detailed functional characterization of malaria-s...

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Bibliographic Details
Main Authors: Prasanna Jagannathan, Ijeoma Eccles-James, Katherine Bowen, Felistas Nankya, Ann Auma, Samuel Wamala, Charles Ebusu, Mary K Muhindo, Emmanuel Arinaitwe, Jessica Briggs, Bryan Greenhouse, Jordan W Tappero, Moses R Kamya, Grant Dorsey, Margaret E Feeney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3887092?pdf=render

Internet

http://europepmc.org/articles/PMC3887092?pdf=render

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