Scavenging of highly reactive gamma-ketoaldehydes attenuates cognitive dysfunction associated with epileptogenesis
Cognitive dysfunction is a major comorbidity of the epilepsies; however, treatments targeting seizure-associated cognitive dysfunction, particularly deficits in learning and memory are not available. Isoketals and neuroketals, collectively known as gamma-ketoaldehydes are formed via the non-enzymati...
Main Authors: | Jennifer N. Pearson, Eric Warren, Li-Ping Liang, L. Jackson Roberts, II, Manisha Patel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-02-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996116302790 |
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