Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells

<p>Abstract</p> <p>In this study we have made novel observations with regards to potentiation of the tumoricidal activity of the oncolytic adenovirus, dl1520 (ONYX-015) in rat glioblastoma cell lines expressing heat shock protein 72 (HSP72) due to permissive virus replication. ONYX...

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Bibliographic Details
Main Authors: Krewet James A, Madara Jonathan, Shah Maulik
Format: Article
Language:English
Published: BMC 2005-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/4/1/12