Regulation of interferon signaling in response to gut microbes by autophagy

The cellular degradative pathway of autophagy prevents unrestrained inflammatory signaling by removing intracellular microbes, damaged organelles, and other factors that trigger immune reactions. Consistent with this function, a common variant of the autophagy gene ATG16L1 is associated with suscept...

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Bibliographic Details
Main Authors: Patricia K. Martin, Ken Cadwell
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Gut Microbes
Subjects:
Online Access:http://dx.doi.org/10.1080/19490976.2019.1614395