Physics, chemistry, and Hirshfeld surface analyses of gamma-irradiated thalidomide to evaluate behavior under sterilization doses

Thalidomide was indicated as a sedative and antiemetic and prescribed for pregnant women. Its tragic teratogenic effects culminated in withdrawal from the market. Since the discovery of its anti-angiogenic and anti-inflammatory actions, thalidomide has been used in the treatment of leprosy and multi...

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Bibliographic Details
Main Authors: Valner A.F.S.N. Mussel, Max P. Ferreira, Maria B.F. Marques, Maria I. Yoshida, Mariana R. Almeida, Bernardo L. Rodrigues, Wagner N. Mussel
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177918300054