Non-toxic polymer nanovectors for improved delivery of dexamethasone

Abstract Dexamethasone (Dex) is a highly insoluble front-line drug used in cancer therapy. Data from clinical trials indicates that the pharmacokinetics of Dex vary considerably between patients and prolonging drug exposure rather than increasing absolute dose may improve efficacy. Non-toxic, fully...

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Bibliographic Details
Main Authors: Benjamin C. Ede, Paraskevi Diamanti, David S. Williams, Allison Blair
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96797-4