Novel Cell Culture Paradigm Prolongs Mouse Corneal Epithelial Cell Proliferative Activity in vitro and in vivo

It has been a long-standing challenge to obtain from cell cultures adequate amounts of mouse corneal epithelial cells (mCEC) to perform transplantation surgery. This limitation is attributable to the passage dependent declines in their proliferative activity. We describe here development of a novel...

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Bibliographic Details
Main Authors: Xiaoya An, Guoliang Wang, Mengyi Jin, Xiaoping Zhou, Shubin Gao, Jingyao Chen, Peter S. Reinach, Zuguo Liu, Yuhua Xue, Cheng Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.675998/full