Stanniocalcin-1 Overexpression Prevents Depression-Like Behaviors Through Inhibition of the ROS/NF-κB Signaling Pathway
Background: Depression is a burdensome psychiatric disorder presenting with disordered inflammation and neural plasticity. We conducted this study with an aim to explore the effect of stanniocalcin-1 (STC1) on inflammation and neuron injury in rats with depression-like behaviors.Methods: A model of...
Main Authors: | Bin Chao, Lili Zhang, Juhua Pan, Ying Zhang, Yuxia Chen, Manman Xu, Shijing Huang |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-06-01
|
Series: | Frontiers in Psychiatry |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.644383/full |
Similar Items
-
Human Tonsil-Derived Mesenchymal Stromal Cells Maintain Proliferating and ROS-Regulatory Properties via Stanniocalcin-1
by: Yoojin Seo, et al.
Published: (2020-03-01) -
Expression and Localization of Stanniocalcin-1 in Bovine Osteoblasts
by: Dong-yang Liu§, Shi-jin Yang§, Zhao-fang Xi, Liming-Wu, Sen Chen, Shi-qi Dong, Jian-lin Wang and Ding-zong Guo*
Published: (2012-05-01) -
Modulation of LPS-induced ROS production and NF-κB nuclear translocation by N-stearoylethanolamine in macrophages
by: A. G. Berdyshev, et al.
Published: (2017-10-01) -
Gene expression analyses identify a relationship between stanniocalcin 2 and the malignant behavior of colorectal cancer
by: Wang J, et al.
Published: (2018-10-01) -
Koumine Suppresses IL-1β Secretion and Attenuates Inflammation Associated With Blocking ROS/NF-κB/NLRP3 Axis in Macrophages
by: Yufei Luo, et al.
Published: (2021-01-01)