Stanniocalcin-1 Overexpression Prevents Depression-Like Behaviors Through Inhibition of the ROS/NF-κB Signaling Pathway

Stanniocalcin-1 Overexpression Prevents Depression-Like Behaviors Through Inhibition of the ROS/NF-κB Signaling Pathway

Background: Depression is a burdensome psychiatric disorder presenting with disordered inflammation and neural plasticity. We conducted this study with an aim to explore the effect of stanniocalcin-1 (STC1) on inflammation and neuron injury in rats with depression-like behaviors.Methods: A model of...

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Bibliographic Details
Main Authors: Bin Chao, Lili Zhang, Juhua Pan, Ying Zhang, Yuxia Chen, Manman Xu, Shijing Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Psychiatry
Subjects:
depression
stanniocalcin-1
reactive oxygen species
NF-κB
inflammation
neural plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.644383/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2021.644383/full

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