Recent data concerning heparanase: focus on fibrosis, inflammation and cancer
Heparanase (HPSE) is a multitasking protein characterized by enzymatic and non-enzymatic activities. By means of its enzymatic activity, HPSE catalyzes the cutting of the side chains of heparan sulfate (HS) proteoglycans, thereby inducing the remodeling of the extracellular matrix and basement membr...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2015-12-01
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Series: | Biomolecular Concepts |
Subjects: | |
Online Access: | https://doi.org/10.1515/bmc-2015-0021 |