Assessment of Polyethylene Glycol-Coated Gold Nanoparticle Toxicity and Inflammation In Vivo Using NF-κB Reporter Mice

Assessment of Polyethylene Glycol-Coated Gold Nanoparticle Toxicity and Inflammation In Vivo Using NF-κB Reporter Mice

Polyethylene glycol (PEG) coating of gold nanoparticles (AuNPs) improves AuNP distribution via blood circulation. The use of PEG-coated AuNPs was shown to result in acute injuries to the liver, kidney, and spleen, but long-term toxicity has not been well studied. In this study, we investigated repor...

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Bibliographic Details
Main Authors: Tzu-Yin Chen, Mei-Ru Chen, Shan-Wen Liu, Jin-Yan Lin, Ya-Ting Yang, Hsin-Ying Huang, Jen-Kun Chen, Chung-Shi Yang, Kurt Ming-Chao Lin
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
gold nanoparticle
PEG surface modification
liver inflammation
reporter imaging
NF-κB
steatosis
Online Access:https://www.mdpi.com/1422-0067/21/21/8158

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https://www.mdpi.com/1422-0067/21/21/8158

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