Decreased ovarian function and autophagy gene methylation in aging rats

Abstract Background Degeneration of ovarian function is an obvious feature of female aging. In addition, studies have shown that autophagy decreases with age, and DNA methylation is a hallmark epigenetic pattern during aging. However, it is not clear whether the expression and DNA methylation of aut...

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Bibliographic Details
Main Authors: Qiuyuan Li, Minghui Cai, Jiao Wang, Qiang Gao, Xiaocheng Guo, Xiaotong Jia, Shanshan Xu, Hui Zhu
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Ovarian Research
Subjects:
Online Access:https://doi.org/10.1186/s13048-020-0615-0