Preclinical safety & toxicity evaluation of pooled, allogeneic human bone marrow-derived mesenchymal stromal cells

Preclinical safety & toxicity evaluation of pooled, allogeneic human bone marrow-derived mesenchymal stromal cells

Background & objectives: Administration of ex vivo-expanded human bone marrow-derived mesenchymal stromal cells (hBMMSC) obtained from single donors has shown therapeutic benefits in both preclinical and clinical studies. In this study, the safety, toxicity and biodistribution profiles of a pool...

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Bibliographic Details
Main Authors: Mathiyazhagan Rengasamy, Pawan Kumar Gupta, Udaykumar Kolkundkar, Gurbind Singh, Sudha Balasubramanian, Swathi SundarRaj, Anoop Chullikana, Anish Sen Majumdar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Indian Journal of Medical Research
Subjects:
Biodistribution - BMMSC - human - single and repeat dose toxicity - teratogenic - toxicity - tumorigenicity
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2016;volume=144;issue=6;spage=852;epage=864;aulast=Rengasamy

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2016;volume=144;issue=6;spage=852;epage=864;aulast=Rengasamy

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