Herb drug interaction: effect of Manix® on pharmacokinetic parameters of pefloxacin in rat model

Herb drug interaction: effect of Manix® on pharmacokinetic parameters of pefloxacin in rat model

Objective: To evaluate the effect of Manix®, the commonly used polyherbal formulation on pefloxacin pharmacokinetic parameters. Methods: Microbiological assay was employed using clinical isolate of Escherichia coli samples from hospitalized patients. Results: Manix® altered the bioavailability param...

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Bibliographic Details
Main Authors: Nduka Sunday Odunke, Okonta Eleje, Abba Chika Christiana, Ihekwereme Chibueze Peter, Ekwedigwe Uchenna
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-05-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Pefloxacin
Manix®
Bioavailability
Escherichia coli
Microbiological assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115303038

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http://www.sciencedirect.com/science/article/pii/S2221169115303038

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