Breastmilk-Saliva Interactions Boost Innate Immunity by Regulating the Oral Microbiome in Early Infancy.

Xanthine oxidase (XO) is distributed in mammals largely in the liver and small intestine, but also is highly active in milk where it generates hydrogen peroxide (H2O2). Adult human saliva is low in hypoxanthine and xanthine, the substrates of XO, and high in the lactoperoxidase substrate thiocyanate...

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Bibliographic Details
Main Authors: Saad S Al-Shehri, Christine L Knox, Helen G Liley, David M Cowley, John R Wright, Michael G Henman, Amitha K Hewavitharana, Bruce G Charles, Paul N Shaw, Emma L Sweeney, John A Duley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4556682?pdf=render