The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells.

The B-MYB transcriptional network guides cell cycle progression and fate decisions to sustain self-renewal and the identity of pluripotent stem cells.

Embryonic stem cells (ESCs) are pluripotent and have unlimited self-renewal capacity. Although pluripotency and differentiation have been examined extensively, the mechanisms responsible for self-renewal are poorly understood and are believed to involve an unusual cell cycle, epigenetic regulators a...

Full description

Bibliographic Details
Main Authors: Ming Zhan, Daniel R Riordon, Bin Yan, Yelena S Tarasova, Sarah Bruweleit, Kirill V Tarasov, Ronald A Li, Robert P Wersto, Kenneth R Boheler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427317?pdf=render

Internet

http://europepmc.org/articles/PMC3427317?pdf=render

Similar Items