Thalamic GABA predicts fine motor performance in manganese-exposed smelter workers.

Overexposure to manganese (Mn) may lead to parkinsonian symptoms including motor deficits. The main inhibitory neurotransmitter gamma-aminobutyric acid (GABA) is known to play a pivotal role in the regulation and performance of movement. Therefore this study was aimed at testing the hypothesis that...

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Bibliographic Details
Main Authors: Zaiyang Long, Xiang-Rong Li, Jun Xu, Richard A E Edden, Wei-Ping Qin, Li-Ling Long, James B Murdoch, Wei Zheng, Yue-Ming Jiang, Ulrike Dydak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3913772?pdf=render