N-Acetyl-l-Cysteine Inhibits Marble-Burying Behavior in Mice

In the present study, we examined the effect of N-acetyl-l-cysteine (NAC), a glutamate-modulating agent, on marble-burying behavior in mice. Fluvoxamine (30 mg/kg, p.o.) and mirtazapine (3 mg/kg, i.p.) significantly inhibited marble-burying behavior without affecting locomotor activity. Similarity,...

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Bibliographic Details
Main Authors: Nobuaki Egashira, Atsunori Shirakawa, Moe Abe, Tomiko Niki, Kenichi Mishima, Katsunori Iwasaki, Ryozo Oishi, Michihiro Fujiwara
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319305286