Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex.

Pathogens that traffic in blood, lymphatics, or interstitial fluids must adopt strategies to evade innate immune defenses, notably the complement system. Through recruitment of host regulators of complement to their surface, many pathogens are able to escape complement-mediated attack. The Lyme dise...

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Bibliographic Details
Main Authors: Brandon L Garcia, Hui Zhi, Beau Wager, Magnus Höök, Jon T Skare
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4725857?pdf=render