Comparative analysis of DNA replication timing reveals conserved large-scale chromosomal architecture.
Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably conserved between human and mouse, uncovering large re...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-07-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2895651?pdf=render |