Is Hypoxia a Factor Influencing PSMA-Directed Radioligand Therapy?—An In Silico Study on the Role of Chronic Hypoxia in Prostate Cancer

Is Hypoxia a Factor Influencing PSMA-Directed Radioligand Therapy?—An In Silico Study on the Role of Chronic Hypoxia in Prostate Cancer

Radioligand therapy (RLT) targeting prostate specific-membrane antigen (PSMA) is an emerging treatment for metastatic castration-resistant prostate cancer (mCRPC). It administrates <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><s...

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Bibliographic Details
Main Authors: Gabriele Birindelli, Milos Drobnjakovic, Volker Morath, Katja Steiger, Calogero D’Alessandria, Eleni Gourni, Ali Afshar-Oromieh, Wolfgang Weber, Axel Rominger, Matthias Eiber, Kuangyu Shi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
hypoxia
radioligand therapy
tumor microenvironment
convection–reaction–diffusion models
dosimetry
radiobiology
Online Access:https://www.mdpi.com/2072-6694/13/14/3429

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https://www.mdpi.com/2072-6694/13/14/3429

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