A multi-layered poroelastic slab model under cyclic loading for a single osteon

Abstract Background An osteon consists of a multi-layered bone matrix and interstitial fluid flow in the lacunar–canalicular system. Loading-induced interstitial fluid flow in the lacunar–canalicular system is critical for osteocyte mechanotransduction and bone remodelling. Methods To investigate th...

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Bibliographic Details
Main Authors: Yaogeng Chen, Wenshuai Wang, Shenghu Ding, Xu Wang, Qun Chen, Xing Li
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BioMedical Engineering OnLine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12938-018-0528-y