A branched biosynthetic pathway is involved in production of roquefortine and related compounds in Penicillium chrysogenum.

Profiling and structural elucidation of secondary metabolites produced by the filamentous fungus Penicillium chrysogenum and derived deletion strains were used to identify the various metabolites and enzymatic steps belonging to the roquefortine/meleagrin pathway. Major abundant metabolites of this...

Full description

Bibliographic Details
Main Authors: Hazrat Ali, Marco I Ries, Jeroen G Nijland, Peter P Lankhorst, Thomas Hankemeier, Roel A L Bovenberg, Rob J Vreeken, Arnold J M Driessen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3680398?pdf=render