Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study.

Choroidal neovascularization (CNV) of the macular area of the retina is the major cause of severe vision loss in adults. In CNV, after choriocapillaries initially penetrate Bruch's membrane (BrM), invading vessels may regress or expand (CNV initiation). Next, during Early and Late CNV, the expa...

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Bibliographic Details
Main Authors: Abbas Shirinifard, James Alexander Glazier, Maciej Swat, J Scott Gens, Fereydoon Family, Yi Jiang, Hans E Grossniklaus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3342931?pdf=render