Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome.

Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome.

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected patients initiating anti-retroviral therapy (ART). Here, we examined monocyte activation by prospectively quantitating pro-inflam...

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Bibliographic Details
Main Authors: Bruno B Andrade, Amrit Singh, Gopalan Narendran, Melissa E Schechter, Kaustuv Nayak, Sudha Subramanian, Selvaraj Anbalagan, Stig M R Jensen, Brian O Porter, Lis R Antonelli, Katalin A Wilkinson, Robert J Wilkinson, Graeme Meintjes, Helen van der Plas, Dean Follmann, Daniel L Barber, Soumya Swaminathan, Alan Sher, Irini Sereti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4183698?pdf=render

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http://europepmc.org/articles/PMC4183698?pdf=render

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