TRPV1 Activation Exacerbates Hypoxia/Reoxygenation-Induced Apoptosis in H9C2 Cells via Calcium Overload and Mitochondrial Dysfunction

TRPV1 Activation Exacerbates Hypoxia/Reoxygenation-Induced Apoptosis in H9C2 Cells via Calcium Overload and Mitochondrial Dysfunction

Transient potential receptor vanilloid 1 (TRPV1) channels, which are expressed on sensory neurons, elicit cardioprotective effects during ischemia reperfusion injury by stimulating the release of neuropeptides, namely calcitonin gene-related peptide (CGRP) and substance P (SP). Recent studies show...

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Bibliographic Details
Main Authors: Zewei Sun, Jie Han, Wenting Zhao, Yuanyuan Zhang, Shuai Wang, Lifang Ye, Tingting Liu, Liangrong Zheng
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:International Journal of Molecular Sciences
Subjects:
ischemia
apoptosis
calcium
mitochondrial
TRPV1 protein
rat
Online Access:http://www.mdpi.com/1422-0067/15/10/18362

Internet

http://www.mdpi.com/1422-0067/15/10/18362

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