MiR-146a-5p targeting SMAD4 and TRAF6 inhibits adipogenensis through TGF-β and AKT/mTORC1 signal pathways in porcine intramuscular preadipocytes

MiR-146a-5p targeting SMAD4 and TRAF6 inhibits adipogenensis through TGF-β and AKT/mTORC1 signal pathways in porcine intramuscular preadipocytes

Abstract Background Intramuscular fat (IMF) content is a vital parameter for assessing pork quality. Increasing evidence has shown that microRNAs (miRNAs) play an important role in regulating porcine IMF deposition. Here, a novel miRNA implicated in porcine IMF adipogenesis was found, and its effect...

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Bibliographic Details
Main Authors: Que Zhang, Rui Cai, Guorong Tang, Wanrong Zhang, Weijun Pang
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Adipogenesis
AKT/mTORC1 signal pathway
MiR-146a-5p
Porcine intramuscular fat
SMAD4
TGF-β signal pathway
Online Access:https://doi.org/10.1186/s40104-020-00525-3

Internet

https://doi.org/10.1186/s40104-020-00525-3

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