Expression of ABCG2 (BCRP) in mouse models with enhanced erythropoiesis

Expression of ABCG2 (BCRP) in mouse models with enhanced erythropoiesis

Haem is a structural component of numerous cellular proteins which contributes significantly to iron metabolic processes in mammals but its toxicity demands that cellular levels must be tightly regulated. Breast Cancer Resistance Protein (BCRP/ABCG2), an ATP Binding Cassette G-member protein has bee...

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Bibliographic Details
Main Authors: Gladys Oluyemisi Latunde-Dada, Abas eLaftah, Patarabutr eMasaratana, Andrew eMcKie, Robert J Simpson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Pharmacology
Subjects:
Iron
hypoxia
BCRP
ABCG2
phenylhydrazine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00135/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00135/full

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