Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine Analog

Methods to reduce the carboxylic acid moiety in 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-oxyl to an alcohol as an intermediate toward the corresponding aldehyde have been explored and an improved method has been developed.

Bibliographic Details
Main Authors: Peter M. Gannett, Edward M. Johnson, Jeannine H. Powell
Format: Article
Language:English
Published: MDPI AG 2000-12-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/5/12/1244/