A Cystine-Rich Whey Supplement (Immunocal®) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

A Cystine-Rich Whey Supplement (Immunocal®) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis

Depletion of the endogenous antioxidant, glutathione (GSH), underlies progression of the devastating neurodegenerative disease, amyotrophic lateral sclerosis (ALS). Thus, strategies aimed at elevating GSH may yield new therapeutics for ALS. Here, we investigated the effects of a unique non-denatured...

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Bibliographic Details
Main Authors: Erika K. Ross, Aimee N. Winter, Heather M. Wilkins, Whitney A. Sumner, Nathan Duval, David Patterson, Daniel A. Linseman
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Antioxidants
Subjects:
Immunocal®
whey protein
oxidative stress
glutathione
cysteine
amyotrophic lateral sclerosis
Online Access:http://www.mdpi.com/2076-3921/3/4/843

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http://www.mdpi.com/2076-3921/3/4/843

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