Lewy Body Variant of Alzheimer's Disease: Selective Neocortical Loss of t-SNARE Proteins and Loss of MAP2 and α-Synuclein in Medial Temporal Lobe

Lewy bodies (LBs) appear in the brains of nondemented individuals and also occur in a range of neurodegenerative disorders, such as dementia with Lewy bodies (DLB) and Parkinson's disease. A number of people with a definite diagnosis of Alzheimer's disease (AD) also exhibit these intraneur...

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Main Authors: Elizabeta B. Mukaetova-Ladinska, John H. Xuereb, Francisco Garcia-Sierra, Jenny Hurt, Herman-J. Gertz, Richard Hills, Carol Brayne, Felicia A. Huppert, Eugene S. Paykel, Magnus A. McGee, Ross Jakes, William G. Honer, Charles R. Harrington, Claude M. Wischik, CC75C Collaboration Group
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2009.151