Alternative Splicing of L-type CaV1.2 Calcium Channels: Implications in Cardiovascular Diseases

Alternative Splicing of L-type CaV1.2 Calcium Channels: Implications in Cardiovascular Diseases

L-type CaV1.2 calcium channels are the major pathway for Ca2+ influx to initiate the contraction of smooth and cardiac muscles. Alteration of CaV1.2 channel function has been implicated in multiple cardiovascular diseases, such as hypertension and cardiac hypertrophy. Alternative splicing is a post-...

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Bibliographic Details
Main Authors: Zhenyu Hu, Mui Cheng Liang, Tuck Wah Soong
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Genes
Subjects:
L-type CaV1.2 calcium channel
alternative splicing
cardiovascular diseases
Online Access:https://www.mdpi.com/2073-4425/8/12/344

Internet

https://www.mdpi.com/2073-4425/8/12/344

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