Synthesis and Antifungal Activity against Fusarium oxysporum of Some Brassinin Analogs Derived from l-tryptophan: A DFT/B3LYP Study on the Reaction Mechanism

An efficient methodology to obtain novel antifungal analogs of brassinin 1 is described. Starting from l-tryptophan 2, N,N′-dialkylthiourea 4, 4-[(1H-indol-3-yl)methylene]-2-sulfanylidene-1,3-thiazolidin-5-one 5 and alkyl (2S)-3-(1H-indol-3-yl)-2-{[(alkylsulfanyl)carbonothioyl]amino}propanoate 6 typ...

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Bibliographic Details
Main Authors: Diego Quiroga, Lili Dahiana Becerra, John Sadat-Bernal, Nathalia Vargas, Ericsson Coy-Barrera
Format: Article
Language:English
Published: MDPI AG 2016-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/10/1349