Propofol protects against blood-spinal cord barrier disruption induced by ischemia/reperfusion injury

Propofol protects against blood-spinal cord barrier disruption induced by ischemia/reperfusion injury

Propofol has been shown to exert neuroprotective effects on the injured spinal cord. However, the effect of propofol on the blood-spinal cord barrier (BSCB) after ischemia/reperfusion injury (IRI) is poorly understood. Therefore, we investigated whether propofol could maintain the integrity of the B...

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Bibliographic Details
Main Authors: Li-jie Xie, Jin-xiu Huang, Jian Yang, Fen Yuan, Shuang-shuang Zhang, Qi-jing Yu, Ji Hu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; spinal cord ischemia reperfusion injury; blood-spinal cord barrier; propofol; matrix metalloprotease-9; nuclear factor-κB; tight junction proteins; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=1;spage=125;epage=132;aulast=Xie

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=1;spage=125;epage=132;aulast=Xie

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