THE ROLE OF CYTOKINE SYSTEM RANKL-RANK-OPG AND CATHEPSIN K IN THE PATHOGENESIS OF OSTEOPOROSIS: ACHIEVEMENTS AND PERSPECTIVES IN THE TREATMENT OF DISEASE

THE ROLE OF CYTOKINE SYSTEM RANKL-RANK-OPG AND CATHEPSIN K IN THE PATHOGENESIS OF OSTEOPOROSIS: ACHIEVEMENTS AND PERSPECTIVES IN THE TREATMENT OF DISEASE

The article presents review of literature dedicated to the contemporary view on the cellular-molecular mechanisms of the bone remodeling and pathogenesis of the osteoporosis. The discovery of the cytokine RANKL-RANK-OPG system and significant role of the cathepsin K in process bone remodeling has ma...

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Bibliographic Details
Main Authors: S. Sagalovsky, P. Kunze, M. Schönert
Format: Article
Language:Russian
Published: ABV-press 2015-10-01
Series:Klinicist
Subjects:
bone remodeling
system rankl-rank-opg
cathepsin k
osteoporosis
denosumab
odanacatib
Online Access:https://klinitsist.abvpress.ru/Klin/article/view/213

Internet

https://klinitsist.abvpress.ru/Klin/article/view/213

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