Phage display demonstrates durable differences in serological profile by route of inoculation in primary infections of non-human primates with Dengue Virus 1

Abstract Natural dengue virus (DENV) infections occur by mosquito bite but how the inoculation route affects the humoral immune response is unknown. We serologically profiled 20 non-human primates (NHP) from a prior study of DENV1 infection where animals were inoculated by mosquito (N = 10) or subcu...

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Bibliographic Details
Main Authors: Jayant V. Rajan, Michael McCracken, Caleigh Mandel-Brehm, Greg Gromowski, Simon Pollett, Richard Jarman, Joseph L. DeRisi
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90318-z