A central role for carbon-overflow pathways in the modulation of bacterial cell death.

Similar to developmental programs in eukaryotes, the death of a subpopulation of cells is thought to benefit bacterial biofilm development. However mechanisms that mediate a tight control over cell death are not clearly understood at the population level. Here we reveal that CidR dependent pyruvate...

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Bibliographic Details
Main Authors: Vinai Chittezham Thomas, Marat R Sadykov, Sujata S Chaudhari, Joselyn Jones, Jennifer L Endres, Todd J Widhelm, Jong-Sam Ahn, Randeep S Jawa, Matthew C Zimmerman, Kenneth W Bayles
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4063974?pdf=render