Wear Particles Promote Reactive Oxygen Species-Mediated Inflammation via the Nicotinamide Adenine Dinucleotide Phosphate Oxidase Pathway in Macrophages Surrounding Loosened Implants

Wear Particles Promote Reactive Oxygen Species-Mediated Inflammation via the Nicotinamide Adenine Dinucleotide Phosphate Oxidase Pathway in Macrophages Surrounding Loosened Implants

Background/Aims: Prosthesis loosening is closely associated with chronic inflammatory cytokine secretion by macrophages, which are activated by wear particles or inflammatory stimulants such as lipopolysaccharide (LPS). Reactive oxygen species (ROS) are critical regulators of inflammation, but their...

Full description

Bibliographic Details
Main Authors: Weishen Chen, Ziqing Li, Ying Guo, Yuhuan Zhou, Ziji Zhang, Yangchun Zhang, Guotian Luo, Xing Yang, Weiming Liao, Chaohong Li, Lingwu Chen, Puyi Sheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
NOX
Apocynin
Wear particles
ROS
Prosthesis loosening
Online Access:http://www.karger.com/Article/FullText/373996

Internet

http://www.karger.com/Article/FullText/373996

Similar Items