The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects

B cells play a central role in the pathogenesis in multiple sclerosis (MS), being involved in the activation of proinflammatory T cells, secretion of proinflammatory cytokines, and production of autoantibodies directed against myelin. Hence, the usage of B-cell-depleting monoclonal antibodies as the...

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Bibliographic Details
Main Authors: Per Soelberg Sorensen, Morten Blinkenberg
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/1756285615601933