The potential role for ocrelizumab in the treatment of multiple sclerosis: current evidence and future prospects
B cells play a central role in the pathogenesis in multiple sclerosis (MS), being involved in the activation of proinflammatory T cells, secretion of proinflammatory cytokines, and production of autoantibodies directed against myelin. Hence, the usage of B-cell-depleting monoclonal antibodies as the...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | Therapeutic Advances in Neurological Disorders |
Online Access: | https://doi.org/10.1177/1756285615601933 |