Interactions of metals and Apolipoprotein E in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia, which is characterized by the neuropathological accumulation of extracellular amyloid plaques and intracellular neurofibrillary tangles (NFTs). Clinically, patients will endure a gradual erosion of memory and other higher order cognitive...

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Bibliographic Details
Main Authors: He eXu, David eFinkelstein, Paul eAdlard
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00121/full