Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects

Sterol 27-Hydroxylase Polymorphism Significantly Associates With Shorter Telomere, Higher Cardiovascular and Type-2 Diabetes Risk in Obese Subjects

Background/objectivesThe pathologic relationship linking obesity and lipid dismetabolism with earlier onset of aging-related disorders, including cardiovascular disease (CVD) and type-2 diabetes (T2D), is not fully elucidate. Chronic inflammatory state, in obese individuals, may accelerate cellular...

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Bibliographic Details
Main Authors: Sofia Pavanello, Laura Angelici, Mirjam Hoxha, Laura Cantone, Manuela Campisi, Amedea Silvia Tirelli, Luisella Vigna, Angela Cecilia Pesatori, Valentina Bollati
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
obesity
cholesterol
HDL
genotyping
cardiovascular diseases
diabetes mellitus type 2
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00309/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00309/full

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