GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress.

GSK3beta-mediated Drp1 phosphorylation induced elongated mitochondrial morphology against oxidative stress.

Multiple phosphorylation sites of Drp1 have been characterized for their functional importance. However, the functional consequence of GSK3beta-mediated phosphorylation of Drp1 remains unclear. In this report, we pinpointed 11 Serine/Threonine sites spanning from residue 634~736 of the GED domain an...

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Bibliographic Details
Main Authors: Chia-Hua Chou, Ching-Chih Lin, Ming-Chang Yang, Chih-Chang Wei, Huei-De Liao, Run-Chin Lin, Wen-Yu Tu, Tsung-Chieh Kao, Ching-Mei Hsu, Jiin-Tsuey Cheng, An-Kuo Chou, Chu-I Lee, Joon-Khim Loh, Shen-Long Howng, Yi-Ren Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3502545?pdf=render

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http://europepmc.org/articles/PMC3502545?pdf=render

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