Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in <i>BRCA1, BRCA2</i>, and <i>TP53</i> Genes in Women with Very Early-Onset (&lt;36 Years) Breast Cancer

Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in <i>BRCA1, BRCA2</i>, and <i>TP53</i> Genes in Women with Very Early-Onset (&lt;36 Years) Breast Cancer

Early age at diagnosis of breast cancer is a known risk factor for hereditary predisposition and some studies show a high risk of contralateral breast cancer in <i>BRCA1</i> carriers diagnosed at very young ages. However, little is published on the risk of <i>TP53</i> carrier...

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Bibliographic Details
Main Authors: Zerin Hyder, Elaine F. Harkness, Emma R. Woodward, Naomi L. Bowers, Marta Pereira, Andrew J. Wallace, Sacha J. Howell, Anthony Howell, Fiona Lalloo, William G. Newman, Miriam J. Smith, D Gareth Evans
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
breast cancer
contralateral
pathogenic variants
early-onset breast cancer
<i>brca1</i>
<i>brca2</i>
tp53
Online Access:https://www.mdpi.com/2072-6694/12/2/378

Internet

https://www.mdpi.com/2072-6694/12/2/378

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