Thermal stability of pepsin: A predictive thermodynamic model of a multi-domain protein

Pepsin is generally used in the preparation of F(ab)2 fragments from antibodies. The antibodies that are one of the largest and fastest growing categories of bio- pharmaceutical candidates. Differential scanning calorimetric is principally suitable method to follow the energetics of a multi-domain,...

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Bibliographic Details
Main Authors: Ali Asghar Rastegari, Behnaz Buzari, Abdol-Khalegh Bordbar
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817300237