Effect of GH/IGF-1 on Bone Metabolism and Osteoporsosis
Background. Growth hormone (GH) and insulin-like growth factor (IGF-1) are fundamental in skeletal growth during puberty and bone health throughout life. GH increases tissue formation by acting directly and indirectly on target cells; IGF-1 is a critical mediator of bone growth. Clinical studies rep...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2014/235060 |