Early Life Stress Effects on the Glucocorticoid - BDNF interplay in the Hippocampus

Early Life Stress Effects on the Glucocorticoid - BDNF interplay in the Hippocampus

Early life stress (ELS) is implicated in the etiology of multiple psychiatric disorders. Important biological effects of ELS are manifested in stress-susceptible regions of the hippocampus and are partially mediated by long-term effects on glucocorticoid and/or neurotrophin signaling pathways. Gluco...

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Bibliographic Details
Main Authors: Nikolaos P Daskalakis, Edo Ronald eDe Kloet, Rachel eYehuda, Dolores eMalaspina, Thorsten M. Kranz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Hippocampus
BDNF
glucocorticoid
TrkB
HPA axis
early life stress
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00068/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00068/full

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