Rapid Differential Detection of Abrin Isoforms by an Acetonitrile- and Ultrasound-Assisted On-Bead Trypsin Digestion Coupled with LC-MS/MS Analysis

The high toxic abrin from the plant <i>Abrus precatorius</i> is a type II ribosome-inactivating protein toxin with a human lethal dose of 0.1–1.0 µg/kg body weight. Due to its high toxicity and the potential misuse as a biothreat agent, it is of great importance to developing fast and re...

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Bibliographic Details
Main Authors: Long-Hui Liang, Yang Yang, Shu Geng, Xi Cheng, Hui-Lan Yu, Chang-Cai Liu, Shi-Lei Liu
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/5/358