Human VRK1 is an early response gene and its loss causes a block in cell cycle progression.

BACKGROUND: In mammalian cells regulatory proteins controlling the cell cycle are necessary due to the requirements of living in a heterogeneous environment of cell-interactions and growth factors. VRK1 is a novel serine-threonine kinase that phosphorylates several transcription factors and is assoc...

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Bibliographic Details
Main Authors: Alberto Valbuena, Inmaculada López-Sánchez, Pedro A Lazo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2241669?pdf=render